All genes were collected from the research papers.
If the publication described a non-human mammalian gene/protein, the homologous human gene was found and included into the catalog.
| EntrezGene Official Symbol |
Official Full Name | EntrezGene Gene ID |
Also known as |
References | PMID | Virus, strain |
In vivo/ in vitro |
Host organism |
Effect | Experiment |
|---|---|---|---|---|---|---|---|---|---|---|
| MAVS | mitochondrial antiviral signaling protein | 57506 | IPS-1 | [Kurhade C et al., 2016] | 26819220 | TBEV strain Hypr | in vivo | mouse | Decreased median survival time [Kurhade C et al., 2016] | Six- to ten-weekold mice were intraperitoneally infected with TBEV [Kurhade C et al., 2016] |
| CD8A | CD8a molecule | 925 | CD8a | [Růžek D et al., 2011] | 21629771 | TBEV, strain Neudoerfl/IRE | in vivo | mouse | Slower development of the disease [Růžek D et al., 2011] | CD8a-/- mice were inoculated subcutaneously with TBEV (100 pfu) Sodium fluorescein (Sigma-Aldrich), was used to detect fluid shifts between the circulation and CNS, which occur when BBB permeability becomes enhanced [Růžek D et al., 2011] |
| TNF | tumor necrosis factor | 7124 | TNF-a | [Tun MM et al., 2014] | 24938868 | TBEV, Oshima strain | in vivo | mouse | Increased mortality rates [Tun MM et al., 2014] | Mice were infected subcutaneously with 104 pfu of Oshima strains and were monitored daily [Tun MM et al., 2014] |
| IL10 | interleukin 10 | 3586 | IL-10 | [Tun MM et al., 2014] | 24938868 | TBEV, Oshima strain | in vivo | mouse | Increased mortality rates [Tun MM et al., 2014] | Mice were infected subcutaneously with 104 pfu of Oshima strains and were monitored daily [Tun MM et al., 2014] |
| TIA1 | TIA1 cytotoxic granule associated RNA binding protein | 7072 | TIA-1 | [Albornoz A et al., 2014] | 24696465 | TBEV, strain Neudoerfl | in vitro, mouse embryonic fibroblast (MEF) | mouse | Increase in TBEV extracellular infectivity [Albornoz A et al., 2014] | MEF TIA-1−/− or their control (MEF WT) were infected with TBEV at an MOI of 2. Cell supernatant collected 24 and 48 h p.i. was used to infect Vero cells to measure virus yields (PFU/ml) from infected MEF TIA-1−/− or infected MEF WT samples |
| TIAL1 | TIA1 cytotoxic granule associated RNA binding protein like 1 | 7073 | TIAR | [Albornoz A et al., 2014] | 24696465 | TBEV, strain Neudoerfl | in vitro, mouse embryonic fibroblast (MEF) | mouse | Decrease in TBEV extracellular infectivity [Albornoz A et al., 2014] | MEF TIAR−/− or their control (MEF WT) were infected with TBEV at an MOI of 2. Cell supernatant collected 24 and 48 h p.i. was used to infect Vero cells to measure virus yields (PFU/ml) from infected MEF TIAR−/− or infected MEF WT samples |