Genes encoding proteins that had direct physical interactions with TBEV virion, TBEV proteins or TBEV RNA

All genes were collected from the research papers.
If the publication described a non-human mammalian gene/protein, the homologous human gene was found and included into the catalog.

EntrezGene
Official
Symbol
Official Full Name EntrezGene
Gene ID
Also
known as
References PMID Virus, strain Host
organism
Interactant:
TBEV
virion or viral
proten or
viral RNA
Method                                                            
ARHGAP25 Rho GTPase activating protein 25 9938 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
ARID2 AT-rich interaction domain 2 196528 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
ARNTL aryl hydrocarbon receptor nuclear translocator like 406 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
BICD1 BICD cargo adaptor 1 636 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
CASK calcium/calmodulin dependent serine protein kinase 8573 [Melik W et al., 2012] 22796133 TBEV Human NS5 [Melik W et al., 2012] in vitro, in vitro, PDZ array membranes [Melik W et al., 2012]
CCDC14 coiled-coil domain containing 14 64770 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 30836 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
EMILIN1 elastin microfibril interfacer 1 11117 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
ENO1 enolase 1 2023 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
FAM184A family with sequence similarity 184 member A 79632 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
FURIN furin, paired basic amino acid cleaving enzyme 5045 [Stadler K et al., 1997] 9343204 TBEV Bovine prM [Stadler K et al., 1997] in vitro,  BHK-21 (Baby hamster kidney) cells [Stadler K et al., 1997]
GIPC1 GIPC PDZ domain containing family member 1 10755 [Melik W et al., 2012] 22796133 TBEV Human NS5 [Melik W et al., 2012] in vitro, in vitro, PDZ array membranes [Melik W et al., 2012]
GOPC golgi associated PDZ and coiled-coil motif containing 57120 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
GRIP2 glutamate receptor interacting protein 2 80852 [Melik W et al., 2012] 22796133 TBEV Human NS5 [Melik W et al., 2012] in vitro, in vitro, PDZ array membranes [Melik W et al., 2012]
GRN granulin precursor 2896 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
HNRNPF heterogeneous nuclear ribonucleoprotein F 3185 HNRPF [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
IL16 interleukin 16 3603 [Melik W et al., 2012] 22796133 TBEV Human NS5 [Melik W et al., 2012] in vitro, in vitro, PDZ array membranes [Melik W et al., 2012]
ITGA3 integrin subunit alpha 3 3675 210 kD polypeptide, alpha 3-chain of human integrin [Protopopova EV et al., 1997] 9499239 TBEV Human TBEV virion [Protopopova EV et al., 1997] in vitro,  human embryonic renal cells, affinity chromatography with polyclonal antiidiotypic antibodies (AIA) as antireceptor antibodies [Protopopova EV et al., 1997]
ITGB3 integrin subunit beta 3 3690 αVβ3–integrin [Zaitsev BN et al., 2014] 25319621 TBEV Human E protein  [Zaitsev BN et al., 2014], in vitro, enzyme immunoassay and optical surface waves-based biosensor measurements [Zaitsev BN et al., 2014]
JAG1 jagged 1 182 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
KAT5 lysine acetyltransferase 5 10524 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
LAMB1 laminin subunit beta 1 3912 beta 1-chain of human integrin (110 kD) [Protopopova EV et al., 1997] 9499239 TBEV Human TBEV virion [Protopopova EV et al., 1997] in vitro,  human embryonic renal cells, affinity chromatography with polyclonal antiidiotypic antibodies (AIA) as antireceptor antibodies [Protopopova EV et al., 1997]
LAMB2 laminin subunit beta 2 3913 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 9863 [Ellencrona K et al., 2009] 19199833 TBEV Human NS5 [Ellencrona K et al., 2009] in vitro, PDZ array membranes [Ellencrona K et al., 2009]
MLPH melanophilin 79083 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
MYH9 myosin heavy chain 9 4627 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
PDE4DIP phosphodiesterase 4D interacting protein 9659 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
PDLIM4 PDZ and LIM domain 4 8572 [Ellencrona K et al., 2009] 19199833 TBEV Human NS5 [Ellencrona K et al., 2009] in vitro, PDZ array membranes [Ellencrona K et al., 2009]
PEPD peptidase D 5184 [Lubick KJ et al., 2015] 26159719 TBEV Human NS5 [Lubick KJ et al., 2015] In vitro, Human Embryonic Kidney 293 (HEK293) cells, Immunoblot analysis following co‐IP(immunoprecipitation) of flavivirus NS5 and PEPD‐GFP [Lubick KJ et al., 2015]
PHAX phosphorylated adaptor for RNA export 51808 RNUXA [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
PHC2 polyhomeotic homolog 2 1912 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
RIMS2 regulating synaptic membrane exocytosis 2 9699 [Ellencrona K et al., 2009] 19199833 TBEV Human NS5 [Ellencrona K et al., 2009] in vitro, PDZ array membranes [Ellencrona K et al., 2009]
RNF125 ring finger protein 12 54941 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
RPSA ribosomal protein SA 3921 LBP, 67 kD laminin receptor, LamR1, laminin receptor 1 [Protopopova EV et al., 1997] 9499239 TBEV Human TBEV virion [Protopopova EV et al., 1997] in vitro, human embryonic renal cells, affinity chromatography with polyclonal antiidiotypic antibodies (AIA) as antireceptor antibodies [Protopopova EV et al., 1997]
LBP, 67 kD laminin receptor, LamR1, laminin receptor 2 [Malygin AA et al., 2009] 19961413 TBEV Human E protein [Malygin AA et al., 2009] in vitro,  enzyme immunoassay and immunoblotting  [Malygin AA et al., 2009]
LBP, 67 kD laminin receptor, LamR1, laminin receptor 3 [Zaitsev BN et al., 2014] 25319621 TBEV Human E protein [Zaitsev BN et al., 2014] in vitro,  combined methods of single-molecule dynamic force spectroscopy (SMDFS), enzyme immunoassay and optical surface waves-based biosensor measurements [Zaitsev BN et al., 2014]
SCRIB scribbled planar cell polarity protein 23513 [Ellencrona K et al., 2009] 19199833 TBEV Human NS5 [Ellencrona K et al., 2009] in vitro, PDZ array membranes [Ellencrona K et al., 2009]
[Werme K  et al., 2008] 18042258 TBEV in vitro,  yeast two-hybrid (Y2H) screen against a human brain cDNA library  [Werme K  et al 2008] Human NS5 [Werme K  et al., 2008]
[Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 6598 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
SPDL1 spindle apparatus coiled-coil protein 1 54908 CCDC99 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
TAF15 TATA-box binding protein associated factor 15 8148 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
TIA1 TIA1 cytotoxic granule associated RNA binding protein 7072 [Albornoz A et al., 2014] 24696465 TBEV Human RNA [Albornoz A et al., 2014] in vitro, human U2OS (Human Bone Osteosarcoma Epithelial Cells) cells, Immunofluorescence, and immunoblot analyses [Albornoz A et al., 2014]
TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 7073 TIAR [Albornoz A et al., 2014] 24696465 TBEV Human RNA [Albornoz A et al., 2014] in vitro, human U2OS (Human Bone Osteosarcoma Epithelial Cells) cells, Immunofluorescence, and immunoblot analyses [Albornoz A et al., 2014]
TJP1 tight junction protein 1 7082 [Ellencrona K et al., 2009] 19199833 TBEV Human NS5 [Ellencrona K et al., 2009] in vitro, PDZ array membranes, immunochemical analysis,  HeLa and MDCK cells [Ellencrona K et al., 2009]
TJP2 tight junction protein 2 9414 [Melik W et al., 2012] 22796133 TBEV Human NS5 [Melik W et al., 2012] in vitro, in vitro, PDZ array membranes [Melik W et al., 2012]
TLR7 toll like receptor 7 51284 [Dillmann C et al., 2016] 26783340 TBEV (FSME-IMMUN -inactivated whole virus vaccine against TBE) Human FSME-IMMUN -inactivated whole virus vaccine against TBE [Dillmann C et al., 2016] in vitro, human plasmacytoid dendritic cells (pDCs) [Dillmann C et al., 2016]
TOM1L1 target of myb1 like 1 membrane trafficking protein 10040 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
TRIM21 tripartite motif containing 21 6737 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
TXNDC9 thioredoxin domain containing 9 10190 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
TYK2 tyrosine kinase 2 7297 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
VIM vimentin 7431 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
VPS11 VPS11, CORVET/HOPS core subunit 55823 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
ZBTB17 zinc finger and BTB domain containing 17 7709 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]
ZCCHC17 zinc finger CCHC-type containing 17 51538 [Le Breton M et al., 2011] 22014111 TBEV (strain 263) Human NS5 [Le Breton M et al., 2011] in vitro, high-throughput yeast two-hybrid screen using human cDNA libraries from liver, brain, spleen and bronchial epithelia [Le Breton M et al., 2011]