Дифференциально экспрессирующиеся гены у крыс НИСАГ и WAG в корковом веществе почек в покое, n=3, p<0.01

Symbol Ratio ISIAH /WAG Acc. # Chr. Mb Definition
Myh14 0,36 XM_001080622.1 1 101,7 Rattus norvegicus myosin, heavy polypeptide 14 (Myh14), mRNA.
Ldha 1,46 XM_001080828.1 1 104,0 Rattus norvegicus lactate dehydrogenase A (Ldha), mRNA.
Fchsd2 0,64 XM_218965.4 1 172,3 Rattus norvegicus FCH and double SH3 domains 2 (predicted) (Fchsd2_predicted), mRNA.
Coq7 0,22 NM_012785.1 1 195,1 Rattus norvegicus coenzyme Q7 homolog, ubiquinone (yeast) (Coq7), mRNA.
Bucs1 2,33 XM_001079043.1 1 196,3 Rattus norvegicus butyryl Coenzyme A synthetase 1 (predicted) (Bucs1_predicted), mRNA.
Nupr1 0,33 NM_053611.1 1 201,8 Rattus norvegicus nuclear protein 1 (Nupr1), mRNA.
Hirip3 1,76 NM_001025725.1 1 205,3 Rattus norvegicus HIRA interacting protein 3 (Hirip3), mRNA.
Bnip3 0,11 NM_053420.2 1 218,2 Rattus norvegicus BCL2/adenovirus E1B 19 kDa-interacting protein 3 (Bnip3), nuclear gene encoding mitochondrial protein, mRNA.
Gstp2 0,44 NM_138974.1 1 226,2 Rattus norvegicus glutathione S-transferase, pi 2 (Gstp2), mRNA.
Eif1ad 2,96 NM_001008305.1 1 227,7 Rattus norvegicus eukaryotic translation initiation factor 1A domain containing (Eif1ad), mRNA.
Slc22a8 1,91 NM_031332.1 1 231,7 Rattus norvegicus solute carrier family 22 (organic anion transporter), member 8 (Slc22a8), mRNA.
Fads1 0,59 NM_053445.1 1 233,2 Rattus norvegicus fatty acid desaturase 1 (Fads1), mRNA.
LOC293871 0,59 XM_219758.3 1 241,8 Rattus norvegicus similar to RIKEN cDNA 2410127L17 (predicted) (LOC293871), mRNA.
Pyroxd2 0,34 NM_001004261.1 1 269,4 Rattus norvegicus pyridine nucleotide-disulphide oxidoreductase domain 2  RGD1303232 (RGD1303232), mRNA.
Poll 0,41 NM_001014168.1 1 272,7 Rattus norvegicus polymerase (DNA directed), lambda (Poll), mRNA.
Rps23 1,80 NM_078617.2 2 19,7 Rattus norvegicus ribosomal protein S23 (Rps23), mRNA.
Bhmt 0,37 NM_030850.1 2 42,4 Rattus norvegicus betaine-homocysteine methyltransferase (Bhmt), mRNA.
Arsb 1,75 XM_345140.2 2 42,6 Rattus norvegicus arylsulfatase B (Arsb), mRNA.
Acot12 2,50 NM_130747.1 2 48,1 Rattus norvegicus acyl-CoA thioesterase 12 (Acot12), mRNA.
Bcas2 0,61 XM_001064236.1 2 225,1 Rattus norvegicus breast carcinoma amplified sequence 2 (predicted) (Bcas2_predicted), mRNA.
Trmt13 0,32 XM_001073185.1 2 237,6 tRNA methyltransferase 13 homolog (S. cerevisiae) (MGC124992), mRNA.
Hs2st1 0,49 XM_001079125.1 2 269,0 Rattus norvegicus heparan sulfate 2-O-sulfotransferase 1 (Hs2st1), mRNA.
Ctbs 1,52 NM_031023.1 2 270,8 Rattus norvegicus chitobiase, di-N-acetyl- (Ctbs), mRNA.
Mmadhc 0,37 NM_001004280.1 3 40,9 Rattus norvegicus methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria  (RGD1303272), mRNA.
Pdk1 0,49 NM_053826.2 3 65,0 Rattus norvegicus pyruvate dehydrogenase kinase, isozyme 1 (Pdk1), nuclear gene encoding mitochondrial protein, mRNA.
RGD1309730 0,56 XM_001071147.1 3 97,7 Rattus norvegicus similar to RIKEN cDNA B230118H07 (predicted), transcript variant 2 (RGD1309730_predicted), mRNA.
Cat 1,75 NM_012520.1 3 100,0 Rattus norvegicus catalase (Cat), mRNA.
Cst3 0,62 NM_012837.1 3 149,6 Rattus norvegicus cystatin C (Cst3), mRNA.
Pxmp4 0,03 NM_172223.2 3 156,5 Rattus norvegicus peroxisomal membrane protein 4 (Pxmp4), mRNA.
Phf20 0,35 XM_001065863.1 3 159,3 Rattus norvegicus PHD finger protein 20 (RGD1305020_predicted), mRNA.
Gng11 0,46 NM_022396.1 4 28,9 Rattus norvegicus guanine nucleotide binding protein (G protein), gamma 11 (Gng11), mRNA.
RGD1562178 1,69 XM_575395.2 4 44,5 Rattus norvegicus similar to Adenylate kinase 2 (predicted) (RGD1562178_predicted), mRNA.
Akr1b10 3,65 NM_001013084.1 4 61,8 Rattus norvegicus aldo-keto reductase family 1, member B10 (aldose reductase) (Akr1b10), mRNA.
Inmt 6,36 XM_347233.3 4 150,0 Rattus norvegicus indolethylamine N-methyltransferase (LOC368066), mRNA.
Retsat 3,65 NM_145084.1 4 165,2 Rattus norvegicus retinol saturase (all trans retinol 13,14 reductase) (Retsat), mRNA.
Chchd4 1,53 NM_001013431.1 4 187,4 Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 4 (Chchd4), nuclear gene encoding mitochondrial protein, mRNA.
Wbp11 0,37 NM_001009661.1 4 234,4 Rattus norvegicus WW domain binding protein 11 (Wbp11), mRNA.
LOC683385 0,54 XM_001066529.1 4 0,3 and 66,1 Rattus norvegicus similar to Insulin-induced gene 1 protein (INSIG-1) (Insulin-induced growth response protein CL-6) (Immediate-early protein CL-6) (LOC683385), mRNA.
Adhfe1 0,06 NM_001025423.1 5 14,2 Rattus norvegicus alcohol dehydrogenase, iron containing, 1 (Adhfe1), mRNA.
Ndufaf6 2,51 XM_232684.3 5 29,0 Rattus norvegicus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 (RGD1309085_predicted), mRNA.
Nbn 2,75 NM_138873.1 5 34,3 Rattus norvegicus nibrin (Nbn), mRNA.
Mrpl50 2,22 XM_342835.2 5 69,3 Rattus norvegicus mitochondrial ribosomal protein L50 (predicted) (Mrpl50_predicted), mRNA.
Bend5 0,60 XM_001063544.1 5 135,1 Rattus norvegicus BEN domain containing 5 (LOC362564), mRNA.
Ccdc30 2,58 XM_001073839.1 5 142,2 Rattus norvegicus coiled-coil domain containing 30 (RGD1305604), mRNA.
RGD1562162 0,20 XR_008163.1 5 152,3 Rattus norvegicus similar to Zgc:56193 (predicted) (RGD1562162_predicted), mRNA.
Hmgcl 0,44 NM_024386.1 5 158,1 Rattus norvegicus 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (Hmgcl), mRNA.
Usp48 0,61 NM_198785.1 5 159,7 Rattus norvegicus ubiquitin specific protease 48 (Usp48), mRNA.
Akr7a3 0,53 NM_013215.1 5 161,5 Rattus norvegicus aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) (Akr7a3), mRNA.
Clcnka 0,49 NM_053327.1 5 163,6 Rattus norvegicus chloride channel Ka (Clcnka), mRNA.
Tas1r1 0,16 XM_342986.2 5 172,8 Rattus norvegicus taste receptor, type 1, member 1 (Tas1r1), mRNA.
Socs5 5,68 XM_575987.2 6 20,7 Rattus norvegicus suppressor of cytokine signaling 5(RGD1564914), mRNA.
Txndc7 0,56 XM_576132.1 6 52,3  Rattus norvegicus thioredoxin domain containing 7 (Txndc7), mRNA.
Ppm1a 0,59 NM_017038.1 6 103,9 Rattus norvegicus protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a), mRNA.
Gpx2 2,62 NM_183403.1 6 109,2 Rattus norvegicus glutathione peroxidase 2 (Gpx2), mRNA.
Zfp410 0,53 XM_001058294.1 6 117,5 Rattus norvegicus zinc finger protein 410 (predicted) (Zfp410_predicted), mRNA.
Ptprb 0,57 XM_235156.4 7 59,4 Rattus norvegicus protein tyrosine phosphatase, receptor type, B (predicted) (Ptprb_predicted), mRNA.
Ly6b 0,18 NM_139257.1 7 116,3 Rattus norvegicus lymphocyte antigen 6 complex, locus B (Ly6b), mRNA.
Ela1 1,79 NM_012552.2 7 140,1 Rattus norvegicus elastase 1, pancreatic (Ela1), mRNA.
Sorl1 0,26 XM_001065506.1 8 44,7 Rattus norvegicus sortilin-related receptor, L(DLR class) A repeats-containing (predicted) (Sorl1_predicted), mRNA.
Tf 0,49 NM_001013110.1 8 111,1 Rattus norvegicus transferrin (Tf), mRNA.
Tmem14a 3,17 XM_343546.3 9 26,2 Rattus norvegicus transmembrane protein 14A (predicted) (Tmem14a_predicted), mRNA.
Rnf149 0,20 XM_343561.3 9 45,9 Rattus norvegicus ring finger protein 149 (Rnf149), mRNA.
Sdpr 4,08 NM_001007712.1 9 54,9 Rattus norvegicus serum deprivation response (Sdpr), mRNA.
Lancl1 0,51 NM_053723.1 9 73,3 Rattus norvegicus lanC (bacterial lantibiotic synthetase component C)-like 1 (Lancl1), mRNA.
Fn1 0,58 NM_019143.1 9 78,7 Rattus norvegicus fibronectin 1 (Fn1), mRNA.
Cldn9 0,39 NM_001011889.1 10 12,8 Rattus norvegicus claudin 9 (Cldn9), mRNA.
Flywch1 4,74 XM_001056224.1 10 12,9 Rattus norvegicus FLYWCH-type zinc finger 1 (RGD1309385), mRNA.
Tmprss8 0,46 NM_199371.1 10 13,2 Rattus norvegicus transmembrane protease, serine 8 (intestinal) (Tmprss8), mRNA.
Wwc1 1,69 XM_220308.4 10 20,5 Rattus norvegicus WW and C2 domain containing 1 (RGD1308329), mRNA.
Gm2a 0,42 NM_172335.2 10 40,3 Rattus norvegicus GM2 ganglioside activator (Gm2a), mRNA.
Spns3 0,45 XM_573133.2 10 58,8 Rattus norvegicus spinster homolog 3 (Drosophila) (RGD1561884), mRNA.
Spata22 0,48 XM_340842.3 10 59,6 Rattus norvegicus spermatogenesis associated 22 (RGD1565378), mRNA.
Pctp 2,88 NM_017225.1 10 77,4 Rattus norvegicus phosphatidylcholine transfer protein (Pctp), mRNA.
Krt19 3,98 NM_199498.1 10 87,8 Rattus norvegicus keratin 19 (Krt19), mRNA.
Ezh1 0,43 XM_220986.4 10 88,9 Rattus norvegicus enhancer of zeste homolog 1 (Drosophila) (predicted) (Ezh1_predicted), mRNA.
Becn1 2,21 NM_053739.1 10 89,0 Rattus norvegicus beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) (Becn1), mRNA.
G6pc 1,50 NM_013098.1 10 89,9 Rattus norvegicus glucose-6-phosphatase, catalytic (G6pc), mRNA.
Hdac5 0,42 XM_213469.3 10 89,9 Rattus norvegicus histone deacetylase 5 (Hdac5), mRNA.
Polg2 9,36 XM_221047.4 10 94,7 Rattus norvegicus polymerase (DNA directed), gamma 2, accessory subunit (predicted) (Polg2_predicted), mRNA.
Apoh 0,18 NM_001009626.1 10 96,4 Rattus norvegicus apolipoprotein H (beta-2-glycoprotein I) (Apoh), mRNA.
Slc5a3 0,09 NM_053715.2 11 35,8 Rattus norvegicus solute carrier family 5 (inositol transporters), member 3 (Slc5a3), mRNA.
Mx2 11,38 NM_134350.2 11 41,5 Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), mRNA.
Tmprss2 15,33 NM_130424.2 11 41,6 Rattus norvegicus transmembrane protease, serine 2 (Tmprss2), mRNA.
Cldn16 0,51 NM_131905.1 11 83,0 Rattus norvegicus claudin 16 (Cldn16), mRNA.
Rfc4 0,55 XM_001056509.1 11 84,4 Rattus norvegicus replication factor C (activator 1) 4 (predicted) (Rfc4_predicted), mRNA.
Comt 0,17 NM_012531.1 11 89,8 Rattus norvegicus catechol-O-methyltransferase (Comt), mRNA.
Txnrd2 0,61 NM_022584.1 11 89,8 Rattus norvegicus thioredoxin reductase 2 (Txnrd2), mRNA.
LOC497685 0,33 XM_579547.1 12 36,1 Rattus norvegicus hypothetical gene supported by NM_032416 (LOC497685), mRNA.
P2rx4 0,32 NM_031594.1 12 41,2 Rattus norvegicus purinergic receptor P2X, ligand-gated ion channel 4 (P2rx4), mRNA.
Rpl6 0,53 NM_053971.1 12 42,7 Rattus norvegicus ribosomal protein L6 (Rpl6), mRNA.
Nme7 0,32 NM_138532.1 13 87,5 Rattus norvegicus non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase) (Nme7), mRNA.
Dcaf6  0,62 XM_213926.4 13 88,5 Rattus norvegicus DDB1 and CUL4 associated factor 6(RGD1561961), mRNA.
Cd48 0,60 NM_139103.1 13 94,7 Rattus norvegicus Cd48 molecule (Cd48), mRNA.
Rrp15 1,94 NM_001009702.1 13 109,8 Rattus norvegicus ribosomal RNA processing 15 homolog (S. cerevisiae) (Rrp15), mRNA.
Ephx2 16,68 NM_022936.1 15 48,8 Rattus norvegicus epoxide hydrolase 2, cytoplasmic (Ephx2), mRNA.
Clu 0,23 XM_001053033.1 15 48,9 Rattus norvegicus clusterin (Clu), mRNA.
RGD1308430 1,66 XM_001054512.1 15 37,2 Rattus norvegicus similar to 1700123O20Rik protein (predicted) (RGD1308430_predicted), mRNA.
Rpl15 3,14 NM_139114.2 15 12,3 Rattus norvegicus ribosomal protein L15 (Rpl15), mRNA.
Jund 1,64 XM_001070425.1 16 20,3 Rattus norvegicus Jun D proto-oncogene (Jund), mRNA.
Nt5dc2 0,43 NM_001009271.1 16 7,1 Rattus norvegicus 5′-nucleotidase domain containing 2 (Nt5dc2), mRNA.
Sncg 0,49 NM_031688.1 16 9,0 Rattus norvegicus synuclein, gamma (breast cancer-specific protein 1) (Sncg), mRNA.
Enpp6 5,36 XM_224853.4 16 48,0 Rattus norvegicus ectonucleotide pyrophosphatase/phosphodiesterase 6 (predicted) (Enpp6_predicted), mRNA.
Slc17a3 0,61 NM_153622.1 17 45,4 Rattus norvegicus solute carrier family 17 (sodium phosphate), member 3 (Slc17a3), mRNA.
Serpinb6a 1,65 NM_199085.1 17 34,1 Rattus norvegicus serine (or cysteine) peptidase inhibitor, clade B, member 6a (Serpinb6a), mRNA.
Serpinb9 0,61 NM_001007732.1 17 34,5 Rattus norvegicus serine (or cysteine) peptidase inhibitor, clade B, member 9 (Serpinb9), mRNA.
LOC682869 1,84 XM_001061265.1 17 5,1 Rattus norvegicus similar to Golgi phosphoprotein 2 (Golgi membrane protein GP73), transcript variant 2 (LOC682869), mRNA.
Isca1 0,51 NM_181626.3 17 7,5 Rattus norvegicus iron-sulfur cluster assembly 1 homolog (S. cerevisiae) (Isca1), mRNA.
RGD1564391 0,08 XM_346945.2 17 7,8 Rattus norvegicus RGD1564391 (predicted) (RGD1564391_predicted), mRNA.
LOC306766 6,54 NM_001014007.1 17 12,7 Rattus norvegicus hypothetical LOC306766 (LOC306766), mRNA.
Tm7sf1 0,39 XM_237907.3 17 92,4 Rattus norvegicus transmembrane 7 superfamily member 1 (predicted) (Tm7sf1_predicted), mRNA.
Akr1c12l1 0,65 XM_001068266.1 17 71,3 Rattus norvegicus aldo-keto reductase family 1, member C12-like 1 (RGD1559604), mRNA.
Akr1c19 0,60 XM_001062695.1 17 71,4  Rattus norvegicus aldo-keto reductase family 1, member C19 (RGD1562954), mRNA.
LOC364763 3,93 XM_344621.2 17 72,2 Rattus norvegicus similar to GTP-binding protein NGB (LOC364763), mRNA.
Cubn 1,54 NM_053332.2 17 82,2 Rattus norvegicus cubilin (intrinsic factor-cobalamin receptor) (Cubn), mRNA.
Tcf4 0,16 NM_053369.1 18 64,5 Rattus norvegicus transcription factor 4 (Tcf4), mRNA.
Smad4 0,40 NM_019275.1 18 68,8 Rattus norvegicus MAD homolog 4 (Drosophila) (Smad4), mRNA.
Es22 0,54 NM_031565.1 19 26,2 Rattus norvegicus esterase 22 (Es22), mRNA.
Nip7 1,93 NM_138847.1 19 50,1 Rattus norvegicus nuclear import 7 homolog (S. cerevisiae) (Nip7), mRNA.
LOC361417 0,14 XM_346974.1 19 49,7 Rattus norvegicus hypothetical LOC361417 (LOC361417), mRNA.
G7c 2,53 NM_212499.1 20 7,1 Rattus norvegicus G7c protein (G7c), mRNA.
RT1-A1 6,09 NM_001008827.1 20 7,5 Rattus norvegicus RT1 class Ia, locus A1 (RT1-A1), mRNA.
Gstt2 0,52 NM_012796.1 20 15,9 Rattus norvegicus glutathione S-transferase, theta 2 (Gstt2), mRNA.
Cd24 0,49 NM_012752.2 20 50,0 Rattus norvegicus CD24 antigen (Cd24), mRNA.
RT1-CE15 8,43 NM_001008838.1 20 4,8 Rattus norvegicus RT1 class I, CE15 (RT1-CE15), mRNA.
Cul4b 0,59 XM_001058651.1 X 124,9 Rattus norvegicus cullin 4B (predicted) (Cul4b_predicted), mRNA.
Tmem27 1,83 NM_020976.1 X 32,5 Rattus norvegicus transmembrane protein 27 (Tmem27), mRNA.

 

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