Human induced pluripotent stem cells are a unique tool for disease modeling in vitro. The development of genome editing technologies and protocols for the directed differentiation of pluripotent stem cells makes it possible to create advanced models.

Our laboratory generated a unique collection of induced pluripotent stem cell lines obtained from patients with hereditary diseases and healthy donors. These lines have been genotyped and characterized in detail using universal standards. Using the CRISPR/Cas9 system, we generate isogenic cell lines and lines carrying transgenes such as genetically encoded biosensors and programmable nucleases.

Here, we post information about the cell and plasmid collection we obtained, as well as stem cell differentiation techniques. We are always ready for mutually beneficial collaboration for the joint solution of complex scientific problems.